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I didn’t actually have to do all of them manually – I wrote a computer script to do a lot of them. The script itself involved a lot of “how many of them can I get automatically this way? How about this way?” but in the end it got most of them, leaving only a couple dozen maybe to do manually. Still took a few days!
So I’m not sure what I’ll find about differences by age, but I’d guess activity level might be one we’d see. Hopefully I’ll get to grips with this this week. If I find anything I’ll post here to let you folks know.
For what it’s worth, Ann, this ended up being a really interesting problem. We are pretty close to having it figured out – should be able to get you an answer tomorrow. But in short, yes, this sample is not from your dog. You were right.
I have an ES too!
You can actually just type whatever you want in to the breed list – if it’s not an option that’s available, just type it anyways. It will go in!
Yes, we are starting with just breed for now. Hard as it is to call breed correctly, it’s still the most straightforward analysis! We’re moving forward with more stuff gradually.
Ellen – thanks for letting us know! I went in as you and updated, and it let me change Boone’s birthdate to 12-28. Please let me know if you have any trouble changing anything else.October 29, 2018 at 5:27 pm in reply to: "Order DNA Kit" for dogs who have already submitted sample? #6893
If you click on that “Order DNA Kit” button it will tell you that you already have an Explorer Level kit, but will offer you the option of a Trailblazer Kit. (We don’t expect many people to be interested in Trailblazer – it’s expensive, but offers very deep sequencing of a dog’s genome.)
Thanks for being one of our early participants!October 29, 2018 at 5:24 pm in reply to: Genetic diversity results + health issues questions #6890
Oh I see – sorry, I should have read more closely! We are all a little frantic today keeping up with all the mail about breed results being in.
So, at the present time we don’t have any way to store or work with that information. But we are actively working on building a way for folks to give us that information through the website. So stay tuned! We do hope it will happen in 2019.October 29, 2018 at 4:59 pm in reply to: Genetic diversity results + health issues questions #6884
Thanks for checking in!
Genetic diversity is a complex measurement. The results we are returning as part of breed ancestry are really a brute force overview and NOT something that should be used to make any assumptions about the dog’s actual genetic diversity overall. We are currently exploring the possibility of providing better diversity results, but there are some technical hurdles to overcome first.
(For the nerdy among you: in order to really say if it is surprising that a dog is homozygous at a particular allele, we have to know the frequency of both versions of that allele in the general population. For example, if 99% of dogs have exactly the same version of a particular gene, and it is super rare to have a different version, then we don’t want to ding a dog as “less diverse” for having two identical copies of that gene. So right now we’re working on getting the frequency of various alleles throughout a large sample of dogs. A really large sample… so the computation time is on the order of months. So that’s where that project stands!)
As for genetic conditions, we are not returning information about those, because we don’t feel comfortable with the validity of the tests available. We are working on giving everyone more information about their dogs beyond just breed – we’re hoping in the next few months to have more results back.
It’s going to be easiest for me to figure this out by email – I’ll send you email now.
Hi, Deborah. I just checked – indeed, we haven’t scanned Riley’s kit in yet. I’m guessing what happened is that she was part of our big push to get our last “old” kits out the door before our changeover to our new website. Then our site was down for the move for several weeks, and this also made it impossible for us to enter newly-arrived kits into the system (our database was down too).
We are working through that backlog of kits now. I’m not worried about her kit getting lost in the mail – but if it was, we’ll send you a new one. I’ll keep a note to check on it and let you know, but feel free to email email@example.com to ask us its status again in a few weeks.
Thanks for checking in, Catherine! I’m going to email you and we’ll get this straightened out that way.
And I’ve made a note – we’ll get those additional poodle breeds on our list; thanks for pointing it out!
Hi, Rob. Yes, things are a little different on the new site! Sorry for the disruption.
From the main page, go to “My Laboratory -> View Laboratory.” This should show you the info on any dogs you have signed up (in your case, just Buddy). Let me know if you have more problems!
-Jessica, PostDoc in Karlsson Lab