Forum Replies Created
Thank you Kristen, well said, we appreciate that!
Unfortunately it does take time for us to fund our participating dogs with the grant money that we have. We continue to apply for more though! The more data the more powerful the research.
In order to combat the wait time issue, we have made Darwin’s Ark into a non-profit, which allows owners to donate, funding their dogs sample to be sequenced right away. This is of course optional.
To learn more about our participation options, please check out our FAQ page.
Great ideas! This is something that is definitely on our radar, but we just have not yet had the time to really get it going.
Hopefully in the near future!
The data is not yet available for download on the website, but we are happy to provide a copy directly. Please email firstname.lastname@example.org to connect with a staff scientist.
Best of luck with your work, and hopefully we can help!October 24, 2019 at 5:00 pm in reply to: "Sample is being sequenced" how long did it take after this? #14721
My apologies, I should have been more specific in my first reply. The wait time can vary depending on how your are participating.
Since Darwin’s Ark is research based , we run strictly off of grant money, limiting how many free participation samples can processed at a time. To combat the wait time issue, we made Darwin’s Ark into a non-profit, creating new participation levels.
Owners choosing the Free Participation Waitlist, will have their dogs DNA sequenced by our grant money. This takes time and is limited, but we continue to keep applying for more to support these samples.
If owners don’t want to wait for grant money, they can choose the Explorer Level where they themselves fund their dogs DNA to be sequenced. The sample goes to the lab right away, and this is where it takes about 90-120 days for results. Owners participating for free can click on “Order DNA Analysis” on their dogs profile ($99.00 if we have sample) if they would rather join the Explorer level.
We have more information about our participation levels on our FAQ, but I hope this helps to better explain the wait.
Thank you very much for your participation and patience.
Hi Ruth, great question!
As the research continues, we will add more to your dogs profile, such as size predictions based on genetics, personality reports and more to come! To find out what we are currently reporting, please check out our Stories tab, where we have a post about our results and what they mean.
If your dogs breed is not currently listed in our reference panel (list found on FAQ) then a portion on the results will likely be called “unknown”. As of right now, we are working on adding more breeds to the panel, and will continue to do so.October 8, 2019 at 2:50 pm in reply to: "Sample is being sequenced" how long did it take after this? #14702
Once the sample arrives at the lab to be sequenced it usually takes around 90-120 days until we received back the raw data. Then we can create and upload your dogs results to his/her profile.
Hope this helps!
Hi Deborah, please email us at email@example.com for personal inquiries about your dog.
We will soon have Malinois along with a few other breeds added to our reference panel!
Currently, Kathleen Morrill our PhD student, is looking into validating and finding the ideal parameters for an updated breed reference panel. This panel will look at more genetic markers and includes several new breeds: American Pit Bull Terrier, Bearded Collie, Belgian Malinois, Chinook, English Shepherd, Entlebucher, Saluki, and Tibetan Mastiff.
Since we are purely a research group, we run only off of grant money. Our team continues to apply for more so that we can sequence the samples that we have waiting on the free participation list. The good news is that we have been able to slowly, but consistently send out free participation samples with the grant money that we have. 🙂
In order to combat this wait time issue, we made Darwin’s Ark into a non-profit so that owners can fund their own dog if they do not want to wait for more grant money to come in.
You are more than welcome to remain participating for free, meaning we will eventually support your dogs sample to be sequenced. The timeline for that is a bit unpredictable though as things like this take time. If you do not want to wait any longer, then we have that option for owners to fund their dogs sample for $99.00 if we have it here at the lab.
I hope this helped! Please let me know if you have any further questions.
As the research continues, our reference panel will expand as more dogs enroll. In order to add a breed to our panel, we need at least 12 unrelated, pure bred individuals.
I did check out database, and we do not yet have any purebred Plott Hounds (at least that have been confirmed by our participants on their profiles). We do have a variety of Coonhounds, but not enough just yet to add into the panel.
Hopefully as more people enroll and check off that their dog is pure, we will be able to start adding Plott an Coonhounds! One way to get this going is to spread the word to owners that might have these purebred dogs to enroll with us.
Thank you, Tracy, for participating and supporting our research. Our endeavor to find out more about our four legged friends is certainly not over yet!
If anyone is curious about what breeds we are currently calling, we have the full list up on our FAQ page. Please note that we are currently working on updating our reference panel with a few more breeds (including APBT!). Once the new breeds are added, we will re-run your dogs data against it and update the results.
Thank you everyone for sharing your dogs results, it is so interesting to see the comparison!
If you are curious about the “unknown” portion in your dogs results, this is the percentage that we could not confidently match to a single breed.
Hi Kate, how interesting that you have Audrey’s sister to compare!
Compared to other genetics tests, such as Embark, they are using 200,000 genetic markers where we are now at 9,000,000 markers used in our genetic studies. We can look much deeper and explore more of the dogs DNA.
Another difference is that they have many more breeds in their reference panel, so they will be able to call more breeds. As our research continues, and more unique breeds enroll with us, we are building up our reference panel. Soon, we will be able to call and add to our list America Pit Bull Terrier, English Shepherd and many more! We will let you know when we update you dogs results when our reference panel is added to.
Thank you everyone for all of your support and contributions to our research! Each day we are working hard, making strides towards better understanding your beloved furry family members!
If you are interested in getting you dog’s full genome sequenced, we do offer that! On our FAQ page we have more information about our Trailblazer Level – $2,199 (discounted to $1,999 upon completion of 10 short surveys).
The canine genome consists of ~ 3 billion bases. Most genetics test for dogs look at 150,000 – 200,000 bases. Our research goes even deeper, as we look at 9 million bases per dog for our genetic studies. For our breed calling, because of existing data available on purebreds, we look at 150,000 but are increasing that number to 1.2 million, thanks to our awesome PhD student Kathleen Morrill! By participants like yourself enrolling your purebreds, you are contributing millions of variants to our database.
As for your question about copper storage liver disease, we are not yet focusing on specific diseases. As Jessica mentioned though, we are working to develop a health portal, so once that is up an running we will likely have a better idea of where the research will go in terms of looking into health.
We currently have one paper out that is related to Darwin’s Ark data that we have published.
Megquier, K.; Genereux, D.P.; Hekman, J.; Swofford, R.; Turner-Maier, J.; Johnson, J.; Alonso, J.; Li, X.; Morrill, K.; Anguish, L.J.; Koltookian, M.; Logan, B.; Sharp, C.R.; Ferrer, L.; Lindblad-Toh, K.; Meyers-Wallen, V.N.; Hoffman, A.; Karlsson, E.K. BarkBase: Epigenomic Annotation of Canine Genomes. Genes 2019, 10, 433.
We will certainly be publishing in peer-reviewed journals as the research continues on!