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Home Page Forums Darwin’s Ark Saint Bernard Genetics: Face markings(Mask) and Rear Dew Claws

This topic contains 6 replies, has 6 voices, and was last updated by kristen johnson 2 kristen johnson 2 2 months, 2 weeks ago.

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  • #5924
    chere peshek
    chere peshek
    Participant

    I recently got my first male St. Bernard puppy from a breeder. Do you know if there is a genetic cause for the rare half mask? Also my puppy has fully formed rear dew claws but his front dew claws were removed shortly after birth. I have read that the rear dew claws are not uncommon in the breed. Is there a gene specifically for the rear dew claws?

    #5925
    kathleen morrill
    kathleen morrill
    Participant

    Hello Chere,

    The classic mask seen in St. Bernard dogs is a pattern called “piebald”. Clarence Cook Little, a dog geneticist, discovered in the 1950s how this coat color pattern is inherited and described it as the “S” spotting locus. Later, three groups of scientists independently found the gene responsible for this pattern: MITF. Elinor Karlsson has found that differences in the DNA around this gene, MITF, seem to result in differences in the extent of the piebald pattern.

    While I cannot say for certain what causes the half mask in St. Bernard’s, I think the gene MITF may be a good candidate for its genetic basis!

    The genetic cause for hind-leg dew claws has been attributed to a few different changes in the gene LMBR1. This gene controls hind-leg development. It has also been involved in human polydactyly — that is, people having extra toes!

    I hope this helps. Let me know if you have any more questions!

    Kathleen

    #5926
    brittney logan
    brittney logan
    Keymaster

    Great question Chere, and thank you Kathleen for your knowledgable reply!

    Just so our participants are aware, Kathleen is a graduate student in the Karlsson lab researching canine genetics!

    #5927
    chere peshek
    chere peshek
    Participant

    Thank you Kathleen.

    Great information. I appreciate the quick response.

    It gives me a great starting point for learning about the inheritance of the mask pattern.

    Chere

    #5928
    amy canoles
    amy canoles
    Participant

    Thank you Kathleen. This is interesting.

    My mixed breed is the first dog I have seen with all 4 dew claws.

    How common are dew claws in dogs? My late dog, also a mixed breed, only had 2.

    #6571
    jhon-leo
    jhon-leo
    Participant

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    #6582
    kristen johnson 2
    kristen johnson 2
    Participant

    So interesting! One of my mixed dogs has all four dew claws and the other only has the front two. I never really thought about dew claws at all until I had two dogs with different ones.

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